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The REW containing variants showed considerably enhanced CDC activity, with the most prominent effects measured at low and intermediate CD20 levels, while the effect of REW waned at higher CD20 levels and increased inherent CDC activity of the antibody variants (Fig

In simple steatosis and early metabolic dysfunction-associated steatohepatitis (MASH), many of the body composition and metabolic features predisposing to MASLD/MASH contribute to decreased GH and IGF-I levels